High transtubular grandient hypokalemia: clinical case and a practical proposal for its approach
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Keywords

Hypokalemia; Bartter Syndrome; Gitelman Syndrome; potassium; electrolytes and hypercalciuria.
Hypokalemia
Bartter Syndrome
hypercalciuria
Gitelman Syndrome
electrolytes

How to Cite

1.
Torres S. R, Rosselli C, Olivares C, Olivares O, Rumpf PM, Pulido Medina C. High transtubular grandient hypokalemia: clinical case and a practical proposal for its approach. Rev. Colomb. Nefrol. [Internet]. 2021 May 27 [cited 2021 Dec. 7];8(2):e498. Available from: http://www.revistanefrologia.org/index.php/rcn/article/view/498

Abstract

Potassium is a predominantly intracelular ion involved in multiple essential functions to maintain celular homeostasis. Therefore, its variations at the plasma level are tightly regulated by the renal and endocrine systems; in addition to being affected by situations such as acidosis, changes in plasma osmolality and concentration of another electrolytes. Hypokalemia is a common electrolyte disorder in clinical practice affected by reporting excessive damage or loss. Its diagnostic approach requires a complete medical history that includes personal pathological and pharmacological history, a specific physical examination with certain conditions like patient´s blood volume and hydration status, as well as the measurement of other electrolytes at the plasma level and occasionally in urine. The thanstubuar potassium gradient is a useful tool to address posible causes. Bartter síndrome is one of the causes of elevated transtubular gradient hypokalemia. 

https://doi.org/10.22265/acnef.8.2.498
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